Search on: 2 OXOISOVALERATE DEHYDROGENASE 
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Descriptor English:   2-Oxoisovalerate Dehydrogenase (Acylating) 
Descriptor Spanish:   2-Oxoisovalerato Deshidrogenasa (Acilante) 
Descriptor Portuguese:   2-Oxoisovalerato Desidrogenase (Acilante) 
Synonyms English:   2 Oxoisovalerate Dehydrogenase
2-Oxoisovalerate Dehydrogenase
Dehydrogenase, 2-Oxoisovalerate
Dehydrogenase, alpha-Ketoisovalerate
alpha Ketoisovalerate Dehydrogenase
alpha-Ketoisovalerate Dehydrogenase  
Tree Number:   D08.811.682.657.350.825
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50621 
Unique Identifier:   D050645 

Occurrence in VHL:
 

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DeCS